Major events in Seattle’s history include the Great Seattle Fire of 1889, which destroyed the central business district (but took no lives);[27] the anti-Chinese riots of 1885–1886;[28] the Klondike gold rush, which made Seattle a major transportation center; the Alaska-Yukon-Pacific Exposition of 1909, which is largely responsible for the layout of the University of Washington campus;[29] the Seattle General Strike of 1919, the first general strike in the country;[30] the 1962 Century 21 Exposition, a World’s Fair;[31] the 1990 Goodwill Games;[32] the APEC leaders conference in 1993, and the WTO Ministerial Conference of 1999, marked by street protests and a series of riots.[33]